Custom Peptides
Cayman Chemical 13C63NItrophenylhydrazIn 10mg
A 13C-labeled derivatizing reagent for carboxylic acids
Cayman Chemical ErtapenmsodIum salt 10mg
A long-acting, broad-spectrum antibiotic that is effective against Gram-positive and Gram-negative bacteria
Cayman Chemical Annaosanchun 10mg
A synthetic sterol and neuroprotective agent; increases the viability of, and the levels of ATP and the mitochondrial membrane potential in, hypoxia-exposed and reoxygenated primary rat cortical neurons at 0.1, 0.3, and 1 µM; prevents glutamate-induced increases in intracellular acidification, lactate levels, and glycolysis rate, as well as inhibits glutamate-induced apoptosis, in primary rat cerebral granule neurons at 10 µM; reduces neurological and neuromuscular deficits and infarct volume in a rat model of MCAO-induced ischemia-reperfusion injury at 0.5, 2, or 10 mg/kg
Cayman Chemical PhosphatIdylserInsoysod 10mg
A mixture of soy phosphatidylserines; comprises 2-10% of total phospholipids in mammals and is enriched in the brain; found mainly on the inner leaflet of the cell membrane; synthesized in the ER and mitochondria; is a precursor to phosphatidylcholine and phosphatidylethanolamine; cofactor for various signaling pathways; externalized during apoptosis as a signal for phagocytes to engulf the cell
Cayman Chemical AM92016hydrochlorIde 10mg
An IKr inhibitor (IC50 = 40 nM in isolated rabbit sinoatrial node cells); selective for IKr over L-type Cav current and If at 1 µM; decreases the diastolic depolarization rate and increases cycle length and action potential duration at full repolarization in isolated rabbit sinoatrial node cells at 50 nM; decreases the QT interval and increases heart rate in anesthetized guinea pigs at 1 mg/kg; decreases the time to first arrhythmia and ventricular fibrillation in ouabain-stimulated guinea pigs at 1 mg/kg
Cayman Chemical 5fluoro PB22 4hdroxIsoqu 10mg
Differs from 5-fluoro PB-22 by having an isoquinoline group attached at its four position in place of the quinoline group; intended for forensic and research purposes
Cayman Chemical 5-hydroxy ThIabendazole 10mg
A major metabolite of thiabendazole; has no effect on the growth of third-stage A. caninum larvae
Cayman Chemical LIxIsenatIdeacetate 10mg
A GLP-1R agonist; binds to CHO-K1 cells expressing human GLP-1R (IC50 = 1.4 nM); inhibits Il-1β- and IFN-γ-induced apoptosis in INS-1 rat pancreatic β-cells at 100 pM; lowers blood glucose levels in an OGTT (ED50 = 0.021 nmol/kg) and decreases blood HbA1c levels in db/db mice
Cayman Chemical Gernylgernylaceton 10mg
An inducer of Hsp expression that increases Hsp70, Hsp22, Hsp27, Hsp90, and Hsp105 levels in various cells and tissues; orally bioavailable and has diverse effects in vivo, including hepatoprotective, neuroprotective, and antiulcerative effects
Cayman Chemical L-CarnItIn-d9chlorIde 10mg
An internal standard for the quantification of L-carnitine by GC- or LC-MS
Cayman Chemical LevobupIvacaInd9hydrochlo 10mg
An internal standard for the quantification of levobupivacaine by GC- or LC-MS
Cayman Chemical L-threo-PPMPhydrochlorIde 10mg
An inhibitor of glucosylceramide synthetase; isomer of D-threo-PPMP; inhibits the growth of MCF-7, MDA-MB-468, and SK-BR-3 breast cancer cells (ED50s = 4, 7, and 6 μM, respectively)
Cayman Chemical LIgustroflavon 10mg
An apigenin triglycoside with diverse biological activities; increases PTH release from rat primary parathyroid gland cells at 1 µM and inhibits calcium influx in HEK293 cells; increases serum PTH, as well as serum and bone calcium levels, in a streptozotocin-induced mouse model of diabetes with osteoporosis at 5 and 20 mg/kg three times per week; reduces increases in the expression and levels of CaSR in the kidney of diabetic osteoporotic mice; decreases infarct volume in a rat model of ischemic stroke at 10, 30, and 60 mg/kg and decreases the levels of the necroptosis-associated proteins RIPK3 and MLKL in the brain of ischemic rats at 30 mg/kg